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It happens when a yeast that naturally lives on the skin grows more than usual
Dynamic regulation of airway surface liquid pH by TMEM16A and SLC26A4 in cystic fibrosis nasal epithelia with rare mutations
Linoleic Acid Metabolite Drives Severe Asthma by Causing Airway Epithelial Injury

It also affects electrophysiological activity, circadian rhythms, and hormonal levels, indicating its broad impact on physiological processes 3

ROS are unstable oxygen-containing molecules that easily react with other molecules in a cell [14] and are generated after physiological dysfunctions or exposure to physical agents, such as ultraviolet rays and heat, chemical factors, environmental toxicants, smoking, alcohol, or even other factors, such as obesity, varicocele, aging, or diabetes [11]
