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Oral supplementation of B12, unlike the injection, must be given every day
You'll probably need to keep up retinol treatment over the long term "patients with PCOS may be more likely to relapse with acne as compared to people without PCOS," Reynolds says

To help them lose weight, people spend $33 million on weight loss products

The basis of this toxicity is likely oxidative stress/damage caused by the production of reactive species (such as hydrogen peroxide and acrolein) during polyamine catabolism
doi: 10.1210/en.2006-0966 89 DeuraIHaradaTTaniguchiFIwabeTIzawaMTerakawaN

Suppresses appetite via the brains hypothalamic centers
