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In contrast, in mice administered with the ROS-responsive P-Mn/TI@mHSA, protein NPs exhibited not only a markedly robust signal but also a more widely distributed pattern within the plaques

Mannervik et al
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Indeed, a decrease in GSH levels contributes to oxidative stress associated with aging and many pathological conditions, including neurodegeneration, inflammation and infections

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity
