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Glutathione provides the source of reducing equivalents for its function

ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis

BBB and BCSFB together form the anatomical BCB to shield brain against potentially toxic substances

doi: 10.1016/j.freeradbiomed.2020.07.013 56 PengX.FengC.WangY

The antioxidant properties of serum albumin will be discussed in the following chapter

Several animal and human studies have reported that zinc supplementation can improve fasting blood glucose levels, fasting insulin levels, and lipid profiles in type 1 and type 2 diabetes patients [95,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115]