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Pejic S, Kasapovic J, Todorovic A, Stojiljkovic V, Pajovic SB

In 2013, Rafeek HidhayathBasha et al

2014;9:e96053

Each addresses a different piece of the PCOS puzzle, which is why they're often combined rather than used in isolation

They reported that patients with NAFLD had significantly higher serum homocysteine levels than healthy controls 24

Phenylalanine hydroxylase transfers one atom from molecular oxygen (O 2 ) into the hydroxyl of tyrosine and the other hydroxylates tetrahydrobiopterin forming an intermediate identified as pterin 4-carbinolamine (also called 4-hydroxypterin or 4-hydroxydihydrobiopterin)