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Systematic reviews and cohort studies on reproductive outcomes after bariatric surgery suggest that sustained weight loss is associated with improved ovulatory function, more regular menstrual cycles, improved fertility, and a reduced risk of endometrial hyperplasia a condition linked to prolonged oestrogen exposure in women with obesity

NAC administration increased brain GSH concentrations by 55% in subjects with PD, and 34% in healthy controls ( n =3)

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Risk factors include the speed and magnitude of weight loss, pre-existing nutritional deficiencies, age, sex (women are more commonly affected), and individual genetic susceptibility