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Numerous preclinical studies have confirmed that the NLRP3 inflammasome pathway is closely related to the development of epilepsy [129, 146]

To determine this change accurately, we need to isolate only changes resulting from the Medicare GME affiliation agreement, and not, for example, an increase in the resident-bed-ratio due to participation in new programs, or due to a change in the number of beds in the denominator

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These elements can carry genes that confer resistance to antibiotics, heavy metals, and other environmental stresses

To determine antibody titers, individual samples determined to be true positives were serially diluted by 20- to 393,660-fold (Fig