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Plasmodium falciparum possesses a classical glutaredoxin and a second, glutaredoxin-like protein with a PICOT homology domain

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Cells 1, 346371

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Acta 1790, 14861500

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doi: 10.1186/1742-2094-10-152 193

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Moreover, at the concentrations tested, NAC was not able to induce in RPE cells an increase of intra- or extracellular GSH, despite being a cysteine prodrug, and cell pretreatment with NAC did not prevent intracellular ROS formation following oxidative insult

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and improve patients quality of life (2,3)

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