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Because the BDNF gene plays a central role in regulating neuronal survival, synaptic plasticity, and the formation of new neural connections, individuals with this genotype typically maintain normal neurotrophic signaling capacity within brain networks responsible for learning, memory, and emotional regulation

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29 Without an accurate PD biomarker, tracking target engagement, monitoring disease progression, and optimizing patient stratification is nearly impossible

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PDA shares the BPC-157 amino acid sequence and has no separate regulatory approval pathway

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