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[DOI] [PMC free article] [PubMed] [Google Scholar] Bierwolf C, Struve K, Marshall L, Born J, Fehm HL

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Hyperglycemia, hyperinsulinemia, or hypoinsulinemia can cause oxidative stress, and reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced by excessive oxidative stress can disrupt the BBB and further affect central nervous system (CNS) function

Nose to brain transport pathways an overview: Potential of nanostructured lipid carriers in nose to brain targeting

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PPARd belongs to nuclear receptor superfamily of ligand-activated transcription factors