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This study was supported by grants from the National Natural Science Foundation of China (82273559 and 82073473), the 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University (ZYJC21036), the Clinical Research Innovation Project, West China Hospital, Sichuan University (2019HXCX10) and Sichuan University-Zigong Special Fund for University-Local Science and Technology Cooperation (2021CDZG-21)