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Moreover, low levels of melatonin in AD patients correlate with the severity of cognitive symptoms and behavioral disorders [105]

Even at the level of the median eminence, specific binding sites for IGF-I have been identified where it acts by inhibiting GHRH secretion [161, 162]

Of the 325 transcripts that are specifically singlet oxygen responsive (296 up- and 29 down-regulated), only 129 showed the same response to the allyl-ITC treatment (120 up- and 8 down-regulated) (Additional file 3D)

Chemotherapy resistance reversion Despite the outstanding improvement achieved in both diagnosis and treatment over the past few decades, the deficiency of effectual early detection techniques and the extremely common establishment of acquired resistance to cisplatin- or carboplatin-based chemotherapy collectively render the survival rate of EOC quite unsatisfactory [7]

Kunda, P