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Description
NNMT inhibitor caused weight loss and reduced adipose tissue mass in DIO mice Since in vitro studies showed 5-amino-1MQ to have high cell permeability, enzyme selectivity, and cell culture efficacy, a sub-chronic (11-day) proof-of-concept in vivo study was conducted to test the effect of NNMT inhibition on obesity in HFD fed mice

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We received 58 comments on the Hospice IDR and SFP proposals

The study also highlighted AOD9604s influence on fat metabolism and energy expenditure, and its interaction with 3-adrenergic pathways [2]

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