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For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.

GHK-Cu is one of the more frequently suggested options because it has a real mechanism and modest supporting evidence for skin parameter improvements

Conversely, if adverse effects are noted, titrating down to 0.5mg per day might be necessary

That said, most clinics typically use dosages ranging from 600mg to 1200mg per session for skin whitening purposes

D., Kashyap, S., Warner, G

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