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Description
Four small molecules [sulfamethoxazole, ketoprofen, MES (4- morpholineethanesulfonic acid), glyphosate], and 4-(2-hydroxyethyl)-1- piperazineethanesulfonic acid (HEPES) were used for the spiking sample, and Acetyl-d3-L-carnitine hydrochloride used as the internal standard in selected reaction monitoring (SRM) analysis was purchased from Sigma-Aldrich (St

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Interestingly, by using intermittent, rather than constant, delivery of MTII in rodents, it is possible to prolong the effects of MC4R agonists to reduce food intake, even if this treatment does not prevent tachyphylaxis (Cote, et al
