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Eukaryotic transcription factors (TFs) are characterized by two core functions: a DNA-binding capacity that recognizes specific sequences (e.g., cis -elements in promoters and enhancers) and a transactivation activity that recruits cofactors to modulate transcription 38,39

Supplementation with high doses of vitamins C and E and fish oil has been found to improve clinical symptoms of patients with schizophrenia and partially restored levels of antioxidants (Pandya et al

In senescence microglia, lactate concentration is elevated, and IB, a negative regulator of NF-B, is phosphorylated and subsequently degraded, leading to activation of the NF-B pathway (Wei L

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