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Specifically, PROTAC 82 degraded ATR with a DC 50 value of 22.9 nM and a D max value of 76% in MV-4-11 cells and showed the ability to inhibit cell proliferation of several AML cells (IC 50 values ranging from 0.111.3 M)

Extinguishing the embers: targeting AML metabolism
Some additional targets directly affected progenitor cell proliferation or differentiation (Fig

One of them might be K-PrivateLabel

doi: 10.1007/s00415-006-0170-7 239
Similarly, iron overload has been reported to attenuate the catalase activity in vitro [73,74]
