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The SLC16A7 gene, that encodes MCT2, is expressed primarily in skeletal muscle, brain, and blood

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Notably, analogous effects have not been consistently demonstrated in males, underscoring the sex-specific nature of neuroendocrine adaptations ( Lactation represents a period of exceptionally high metabolic demand during the mammalian life cycle

For instance, considering the occurrence of maculopathy and progressive retinal degeneration among patients with clbC and, to some extent, patients with cblD, interestingly, such conditions do not manifest in patients with mutations in the other genes associated with VitB12 metabolism [50]