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Future of toxicology metabolic activation and drug design: challenges and opportunities in chemical toxicology

In particular, elaborated LPS present on 579 appears to be correlated with increased pro-inflammatory cytokines including CXCL-8 ( Figure 3 ), TNF-, and IL-6 ( Figure 5 )

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Advanced analytical procedures including LCMS screening, heavy metal analysis, endotoxin testing, and sterility verification are routinely performed across commonly studied compounds

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