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Overexpression of cMOAT (MRP2/ABCC2) is associated with decreased formation of platinum-DNA adducts and decreased G2-arrest in melanoma cells resistant to cisplatin

The Bcl-2 family plays a crucial regulatory role in apoptosis, involved in both mitochondrial and some extrinsic apoptotic pathways

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To determine the protein concentration UV absorption, absorption in the UV region of the spectrum will be measure, and the concentration will be calculated according to the Beer-Lambert law, where extinction coefficient and path length are constant

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Phan, L, Jabbour, EJ, Antonoff, MB , Jain, N, Lin, P, Moran, C, Pemmaraju, N