are glutamate and glutathione connected The Role of Metabolism in Chronic Illness Development Its Potential Use as a Novel Therapeutic Target Glutathione synthesis from glycine and
Description
Yes glutathione and vitamin C work synergistically

Compared with FeSAN, the redox peak intensity of TMB in the presence of pFeSAN was much stronger, indicating more available active sites of pFeSAN for more efficient TMB oxidation

The honest answer is that results are gradual

This effect underlies the reports of ascorbate toxicity in mammalian cell cultures and the low (or lack of) ascorbate addition to culture media [3], [8], [27]

I had an advanced stage of adrenal fatigue and within a few months I was nearly back to normal

This includes antibiotics and chemotherapy too
