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Additionally, the rats in the minimal loading group received a steel-orthosis around their right hindlimb directly after surgery, as previously described 24

Figure 5: A) Time spent below range, time in range, time above high range, and time in tight range

Use a separate syringe for each and inject at different sites

Researchers continue to study its mechanisms and potential applications, but it has not been approved by any major regulatory body (FDA, EMA, INVIMA) as a therapeutic drug

Methotrexate can cause hepatotoxicity, leading to insufficient drug tolerance (Wang et al., 2018)