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The underlying mechanism why the compound exhibited the selective cytotoxicity toward tumor cells over non-tumor cells are not fully understood, but it might have reflected the alterations of GST activities in the cells 30 , and the detailed study along this line is currently ongoing

Its efficacy in improving insulin sensitivity, reducing serum androgens, and modulating chronic inflammation have made berberine a subject of interest in PCOS research

Pharmacology of albuterol, a short-acting -adrenergic receptor agonist (SABA), and a frontline bronchodilator in the treatment of asthma

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However, further studies are needed to identify the relevant mechanisms of ferroptosis

Side effects are typically mild, temporary, and manageable