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Evaluation and Staging of Liver Fibrosis Rationale for Staging Liver Fibrosis Hepatic fibrosis is a dynamic scarring process that occurs over time in patients with chronic HCV and can lead to cirrhosis.[9,10] Staging liver disease (or determining fibrosis severity) is best performed before starting HCV treatment because that is when these tests have been validated
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Major changes in complex I activity in mitochondria from aged rats may not be detected by direct assay of NADH:coenzyme Q reductase
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