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-Arrs were shown to interact more transiently with 1 -AR than 2 -AR in response to agonist-stimulated cells, possibly due to weakened phosphorylation of 1 -AR, which in turn will make the interaction of -Arrs with the 1 -AR too weak to recruit ubiquitinating enzymes (Liang and Fishman, 2004)

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Results from Figure 2A confirmed that FOXO4-DRI killed the cells through inducing apoptosis