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Injection volume must also be carefully controlled, as animal studies indicate that reducing the volume can lower the risk of nucleus pulposus protrusion
doi: 10.1093/jac/dkad256 308 ParkJ.SonH
Meanwhile, CUL4B overexpression elevated the levels of Ki67, CUL4B, Fibronectin, c-MYC, and NANOG, and decreased E-cadherin expression
Thirdly, the lack of effective and specific drugs that can safely induce ferroptosis in cancer cells poses an additional challenge
