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Description
1st reaction: conversion of glucose to glucose-6 phosphate
[PMC free article: PMC470750] [PubMed: 15210959] 691
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Y-position cysteine substitution in type I collagen (alpha1(I) R888C/p.R1066C) is associated with osteogenesis imperfecta/EhlersDanlos syndrome phenotype
B.KimM.KimS
This can happen from normal aging (we lose 10-20% of collagen per decade after 30) or by over-stretching the collagen layer and creating rips in it
