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doi: 10.3389/falgy.2026.1771105 Received 18 December 2025 Revised 17 February 2026 Accepted 20 February 2026 Published 12 March 2026 Volume 7 - 2026 Edited by Hasan Bayram, Ko University, Trkiye Reviewed by Zeynep Celebi Sozener, Ankara City Hospital, Trkiye Nuray Uslu Kizilkan, Ko University, Trkiye Updates Copyright 2026 Pilat, Hiremath, Wechsler, Dellon, Choksi and Buendia

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From a clinical evaluation perspective, SDF can often be regarded as one of the comprehensive readout indicators of oxidative stress load, but its upstream driving factors may be multi-sourced, requiring joint interpretation with inflammatory and oxidative stress markers