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B12 also downregulated CSF2 ( P = 0.0071) and CXCL10 ( P = 0.0205) in leukocytes from impaired individuals, although these genes were not differentially regulated when compared to the non-impaired group

SIRT3, as a deacetylase in mitochondria, modulates the transcription of mitochondrial in response to oxidative stress

This delivery method is particularly useful for people who struggle to absorb B12 from food or supplements

These mechanisms help maintain genomic stability and prevent mutations that could lead to diseases such as cancer

Rasmussen et al., 2016
