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Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose

Goal: Support glycemic control, weight management, and metabolic health through dual incretin receptor activation [2]

You may test for B12 in the blood, and you have enough B12, says Begdache

Absorption and Storage of Vitamin B12 Once administered, vitamin B12 is absorbed into the bloodstream and stored primarily in the liver

In particular your therapist will encourage you to specifically stretch your piriformis muscle by sitting in a chair or on the ground and crossing the ankle of your affected side over your other knee

This makes B12 supplementation extremely safe, with a low risk of toxicity