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The delayed gastric emptying is most pronounced during the initial weeks of therapy and during dose escalation periods

Look at the tissue, under a microscope, plus strength tests

Importantly, these effects occurred at rates similar to placebo groups, suggesting that many cases represented background occurrence rather than treatment-specific effects

The logic is to front-load exposure while the tissue is remodeling, then taper to a maintenance rhythm that sustains the effect at a fraction of the vial cost

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