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Interconnections between OxS, T2D Risk Factors, and GSH Metabolism Insulin resistance and impaired beta-cell secretion of insulin both contribute to hyperglycemia-induced OxS and diabetic complications [83]

Disulfiram, which was originally used as an antialcoholism drug, has been repurposed to inhibit ALDH and disrupt redox balance in CSCs, leading to increased sensitivity to chemotherapy and radiotherapy

Articles start with a case presentation (500 words maximum), and a discussion of the underlying condition follows (1000 words maximum)

Neurobiol Aging 1997

10.1016/j.bbagen.2012.08.003 122 MayiA

while this risk is less relevant for injectable forms, caution is still advised in patients with reactive airway diseases