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Hemolytic anemia may be more prevalent in patients with both MTHFR and B12 deficiency

doi: 10.1007/s12325-020-01474-z

However, more recent findings suggest NAD+ therapy might work even better when paired with a compound called 5-Amino-1MQ

The primary difference between the two forms is the molecule attached to the cobalamin (B12) molecule

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Your healthcare provider will monitor you, especially with the first dose