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conversely, a bias toward lipid synthesis increases Th17 cell differentiation, exacerbating inflammation

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While pre-existing immunity against Ad5 is reportedly widespread, its clinical application continues and moreover, alternative ChAdOx1 with low human seroprevalence have been derived for use as vaccine platforms 38,39

Subsequently, with the increase in mitochondrial membrane potential, the mitochondria are depolarized, and large amounts of mtROS are generated[115, 116]
