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Linus Pauling Institute Oregon State University Updated in November 2013 by: Giana Angelo, Ph.D

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Acetaminophen hepatotoxicity: An updated review

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and Ph.D

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Author contributions JP: Visualization, Formal analysis, Writing review & editing, Writing original draft

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N,Nbis-(2-mercaptoethyl) isophthalamide (NBMI), a lipophilic thiol-based chelator with selective affinity for ferrous iron, has demonstrated superior brain chelation efficacy in a mouse model of brain iron overload, making it a promising candidate for IN formulations if its solubility limitations can be addressed (Cheng et al., 2022)

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