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Synergistic antioxidant mechanisms While immune regulation and inflammatory pathway suppression represent core anti-inflammatory actions of PDEVs, mounting evidence suggests that their antioxidant capacity plays an equally critical, synergistic role in mitigating inflammatory diseases

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Acknowledgements Work in T.P.s laboratory was supported by NIH grants (R37CA222504, R01CA227649, R01CA283049, R01CA262562 and R01CA297605) and an American Cancer Society Research Scholar Grant (RSG-17-200-01TBE)