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Gustafsson H, Sderdahl T, Jnsson G, Bratteng JO, Forsby A
During the first step that is considered rate limiting [77], -glutamyl cysteine is produced from l-glutamate and cysteine in the presence of GCL
Kynurenine can be further degraded into different metabolites, like quinolinic acid (degraded to nicotinamide adenine dinucleotide- NAD + ) and picolinic acid, which have distinct effects
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That distinction affects consent, safety monitoring, and accountability
