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Meanwhile, Nrf2 regulates the production of mitochondrial ROS by enhancing the biosynthesis of glutathione and the activity of glutathione reductase, up-regulating the enzymes in the pentose phosphate pathway, and regulating the expression level of mitochondrial antioxidant enzymes, thereby protecting mitochondria from oxidative damage (Ebrahimy et al., 2022

It also helps you feel energised, balanced, and at your best

RSC Adv 14(23):1600116023 Das S, Mondal S, Ghosh D (2024) Carbon quantum dots in bioimaging and biomedicines

This could explain why the activity of rhGPx3 mutant using H 2 O 2 as oxidizing substrate was in the same order of magnitude as that of human native GPx4 (34.8 U/mg) 9 and GPx4 mutant with all Cys converted to Ser (14.0 U/mg) 16 , while it was much lower than that of native GPx4 (64.6 U/mg) and the GPx4 mutant (24.6 U/mg) in the case of using PLPC-OOH as the oxidizing substrate

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