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How This Works SLU-PP-332 is a synthetic small molecule (not a peptide) that acts as a pan-agonist of the estrogen-related receptors ERR, ERR and ERR, with strongest activity at ERR [1] [2]

Glutathione plays a key role in stimulating collagen synthesis by reducing free radicals that damage collagen-producing cells

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As a CPP, FOXO4-DRI differs from these by being designed around a specific amino acid sequence in a molecular target only mildly expressed in most normal tissues (see e.g

Overall safety profile: Pooled trial data showed no meaningful rise in overall adverse events versus placebo [6] [7]

Theranostics 7 , 10361046 (2017)