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Alterations in the Gut-Microbial-Inflammasome-Brain Axis in a Mouse Model of Alzheimers Disease

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[DOI] [PubMed] [Google Scholar] 44.Yeboah J., Crouse J.R., Hsu F.-C., Burke G.L., Herrington D.M

Additionally, the mutant huntingtin protein can impair the function of the transcription factor PGC-1, which is crucial for the regulation of antioxidant defenses and mitochondrial biogenesis

(That ensures an accurate worst case reading of, in particular, metals like copper and lead, which can leach from pipes and concentrate in the stagnant water overnight)