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Suppression of NLRP3 inflammasome by dihydroarteannuin via the HIF-1 and JAK3/STAT3 signaling pathway contributes to attenuation of collagen-induced arthritis in mice

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4816 Informing local policy through an audit of the assessment, management and outcomes of intermediate and high risk patients with pulmonary embolism Julia Harrington 1 , Danielle Hannah 1 , Jun Ki Jeon 1 , Karwai Tsang 1 , Lara Roberts 1 , Tasneem Pirani 2 1 Kings College Hospital 2 Kings college hospital Kings College Hospital, [email protected] Abstract Introduction: In the assessment and management of patients with acute pulmonary embolism (PE), risk stratification can provide information that helps guide therapeutic decision-making and detection of deterioration

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