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28,29 A 2023 systematic review (N = 34 studies) evaluated the effect of CFTR correctors (e.g., elexacaftor, tezacaftor) with or without a potentiator (e.g., ivacaftor) on clinically important benefits in patients with Class II CFTR mutations (most often F508del) in CF patients of any age
coerulea , which contains respectively 38 and 29 GSTFs vs 26 and 24 GSTUs ( P
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