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This altogether suggests that utilization of glucose as fuel for the TCA cycle is impaired in Nf1 Myf5 muscle, thus fatty acids as alternative energy source need to be used

Indeed, hepatic lipid metabolism deregulation was shown to alter the composition of the phospholipids within the ER and thus perturb protein synthesis [64]

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The country announced emergency approval, though no Phase III data was included in the announcement

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