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1 Introduction In recent years, cancer immunotherapy has advanced substantially, shifting from nonspecific immune activation toward more precise strategies such as immune checkpoint blockade (ICB) ( Salmonella ( Salmonella enterica serovar Typhimurium ), have recently regained high interest due to their special biological characteristics ( Attenuated Salmonella is a facultative anaerobe that has a natural propensity to colonize tumors, invade them, and cross biological barriers that are generally impermeable to traditional chemotherapeutic agents ( in vitro tumor models) and process those signals using multilayered genetic circuits to perform precise therapeutic actions in vivo ( This report aims to provide a comprehensive overview of the recent progress and emerging applications of attenuated Salmonella in cancer therapy

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Tudor, M., Jandric, I., Marovic, A., Gjurasin, M., Perovic, D., Radic, B., Blagaic, A

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The average EC concentration in the PM2.5 concentration was 24 g/m 3 , which is approximately 20% higher than the annual mean concentration limit of 20 g/m 3 and comparable to data recorded in Zabrze (city in southern Poland) by 54 equal to the highest 9.6 g/m 3 and the lowest 3.9 g/m 3 respectively