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For the cell death inhibitor (Fer-1, NEC-1, Z-VAD, DIS, and 3-ME) addition assay, cells were pretreated with each inhibitor (both use 10 M) for 3 h, then PQS was added

Concordantly, immunoblot staining showed detectable caspase-1 only in sensitized differentiated urothelia (Fig

An excess of ROS may cause the oxidation of macromolecules and organelles in the body, leading to oxidative stress

163 ThomasB.BealM

[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Soto-Martin EC, Warnke I, Farquharson FM, et al