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A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

PMID: 27167460

It shows in Domain-1 the thioredoxin canonical folding, with the three parallel beta-sheets (124) and one antiparallel (3)

Vet Rec 2012;170:179-184

Bernstein and his colleagues are currently working with NCIs Clinical Therapy Evaluation Program in hopes of launching a clinical trial of infigratinib for people with SDH-deficient GIST

7D): H 2 O 2 increased lipid peroxidation in nsSiRNA cells, but no further increase was noted in the H 2 O 2 -treated GPx1-KO cell (i.e., where baseline was elevated)