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FIGURE 9 4 Discussion In this meta-analysis, we showed that LC supplementation did not significantly change serum lipid levels, including TG, TC, HDL, LDL, or VLDL

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Stojkovic M, Machado SA, Stojkovic P, Zakhartchenko V, Hutzler P, Goncalves PB, Wolf E

Written informed consent was obtained from all of the participants or their families

The results, however, seem to have a far more important diagnostic implication in that although free carnitine and short-chain acylcarnitine are distributed equally between plasma and blood cells, long-chain acylcarnitines are more associated with the latter
If the condition is not correctly diagnosed and no carnitine is supplemented, progressive heart failure eventually leads to transplantation or death
