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In the study of immuno-oncology, the immune checkpoint is an important cellular pathway to maintain normal immune response and protect tissue from immune activation damage, and its checkpoint dysregulation is a key marker for the study of an immune resistance mechanism

Cancers (2020) 12(6):122

Methylsulfonylmethane and mobilee prevent negative effect of IL-1 in human chondrocyte cultures via NF-B signaling pathway

doi: 10.1016/j.intimp.2021.108272

Lancet (2015) 386(9996):896912

McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A, et al
