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In a methicillin-resistant Staphylococcus aureus (MRSA) infection model, mice treated with spermidine exhibited significantly improved survival rates and enhanced bacterial clearance, providing robust experimental evidence for spermidines potential application in treating infectious diseases and laying the groundwork for its clinical use as an immunomodulator (116)

While the causes of this condition are complex, recent research has suggested that excess vitamin B12 intake may play a significant role