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[150] demonstrated that S-glutathionylation of FAS by GSTP stimulates apoptosis of pulmonary epithelial cells, which may result in pulmonary fibrosis

Lipid ROS activates MAPK and NF-B signaling pathways in M1 macrophages, promoting inflammation

Surviving a greater number of pathogens has allowed these ancestral haplotypes to be inherited from generation to generation, but with the disadvantage that those older pathogens with which they have coexisted have also acquired resistance against them via co-evolution of their evasion mechanisms [171, 183]

onlinelibrary.wiley.com, doi:10.1002/pros.20850

Excessive hepatic lipid accumulation has long been proposed to impair insulin signaling pathway and promote insulin resistance

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